Teitl: Data underpinning "N-Cyanation of Secondary Amines using Trichloroacetonitrile"
Dyfyniad
Ayres JN, Ling KB, Morrill LC (2016). Data underpinning "N-Cyanation of Secondary Amines using Trichloroacetonitrile". Cardiff University. https://doi.org/10.17035/d.2016.0011295237
Hawliau Mynediad: Gall data fod ar gael yn rhad ac am ddim yn amodol ar briodoli
Dull Mynediad: I anfon cais i gael y data hwn, ebostiwch opendata@caerdydd.ac.uk
Manylion y Set Ddata
Cyhoeddwr: Cardiff University
Dyddiad (y flwyddyn) pryd y daeth y data ar gael i'r cyhoedd: 2016
Fformat y data: .txt, .inmr, .info, .par, .xml, .pdf, .temp, .back, .jpg, .ispd
Meddalwedd ofynnol: An appropriate NMR processing software is require for raw NMR data files.
Amcangyfrif o gyfanswm maint storio'r set ddata: Llai na 100 megabeit
Nifer y ffeiliau yn y set ddata: 1608
DOI : 10.17035/d.2016.0011295237
DOI URL: http://doi.org/10.17035/d.2016.0011295237
Related URL: http://blogs.cardiff.ac.uk/themorrillgroup/
A one-pot N-cyanation of secondary amines has been developed using trichloroacetonitrile as an inexpensive cyano source. A diverse range of cyclic and acyclic secondary amines can be readily transformed into the corresponding cyanamides in good isolated yields, with the method successfully utilised in the final synthetic step of a biologically-active rolipram-derived cyanamide. This approach exhibits distinct selectivity when compared to the use of highly toxic cyanogen bromide.
Disgrifiad
Herein we include all underpinning data for this publication, including:
1H, 19F and 13C NMR raw data files
IR spectra
HRMS spectra
Research results based upon these data are published at http://10.1021/acs.orglett.6b02775
Prosiectau Cysylltiedig
- N-Cyanation of Secondary Amines using Trichloroacetonitrile (01.10.2015 - 30.09.2018)