Title: Electrochemical Alkene Azidocyanation via 1,4-Nitrile Migration: data
Citation
Seastram A, Hareram MD, Knight TB, et al. (2022). Electrochemical Alkene Azidocyanation via 1,4-Nitrile Migration: data. Cardiff University. https://doi.org/10.17035/d.2022.0214744028
Access Rights: Creative Commons Attribution 4.0 International
Access Method: https://doi.org/10.17035/d.2022.0214744028 will take you to the repository page for this dataset, where you will be able to download the data or find further access information, as appropriate.
Dataset Details
Publisher: Cardiff University
Date (year) of data becoming publicly available: 2022
Data format: .txt, .inmr, .info, .par, .xml, .pdf, .temp, .back, .jpg, .ispd
Software Required: An appropriate NMR processing software is required for raw NMR data files
Estimated total storage size of dataset: Less than 1 gigabyte
DOI : 10.17035/d.2022.0214744028
DOI URL: http://doi.org/10.17035/d.2022.0214744028
Related URL: http://blogs.cardiff.ac.uk/themorrillgroup/
An electrochemical method for the azidocyanation of alkenes via 1,4-nitrile migration has been developed. This organic oxidant free method is applicable across various alkene containing cyanohydrins, and provides access to a broad range of synthetically useful 1,2-azidonitriles (28 examples). This methodology was extended to an electrochemical alkene sulfonylcyanation procedure, as well as to access a trifunctionalized hexanenitrile from a malononitrile starting material. The orthogonal derivatization of the products was also demonstrated through chemoselective transformations. Analysis of reaction products from this methodology resulted in the following data: 1H, 19F and 13C NMR raw data files IR spectra High resolution mass spectrometry spectra. Research results based upon these data are published at http://doi.org/10.1039/D2CC02958H
Description
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