Title:    B(C6F5)3 Catalyzed Diastereoselective and Divergent Reactions of Vinyldiazo Esters with Nitrones: Synthesis of Highly Functionalized Diazo Compounds - data

Citation
Stefkova K, Guerzoni M, van Ingen Y, et al.  (2023). B(C6F5)3 Catalyzed Diastereoselective and Divergent Reactions of Vinyldiazo Esters with Nitrones: Synthesis of Highly Functionalized Diazo Compounds - data. Cardiff University. https://doi.org/10.17035/d.2023.0236343549

Dataset Details

Publisher: Cardiff University

Date (year) of data becoming publicly available: 2023

Data format: .pdf

Software Required: Software to visualise NMR and X-ray data e.g. Mercury/MNova

Estimated total storage size of dataset: Less than 100 megabytes

DOI : 10.17035/d.2023.0236343549

DOI URL: http://doi.org/10.17035/d.2023.0236343549

Description

We report a mild, transition-metal free, highly diastereoselective Lewis acid catalyzed methodology towards the synthesis of isoxazolidine-based diazo compounds, from the reaction between vinyldiazo esters and nitrones. Interestingly, the isoxazolidine products were identified to have contrasting diastereoselectivity to previously reported metal catalyzed reactions. Experimental procedures, full characterization of products, copies of ¹H, ¹³C, ¹⁹F NMR spectra, copies of mass spectra, and the X-ray crystallographic structures are included.

Research results based upon these daa are published at https://doi.org/10.1021/acs.orglett.2c04198