Title: Amplifying Solventless Synthesis: One-pot Multistep Mechanochemical Synthesis of Fluorinated Pyrazolones

Citation
Howard JL, Nicholson W, Sagatov Y, et al. (2017). Amplifying Solventless Synthesis: One-pot Multistep Mechanochemical Synthesis of Fluorinated Pyrazolones. Cardiff University. https://doi.org/10.17035/d.2017.0038572887

Dataset Details

Publisher: Cardiff University

Date (year) of data becoming publicly available: 2017

Data format: txt, .inmr, .info, .par, .xml, .pdf, .temp, .back, .jpg, .ispd

Software Required: An appropriate NMR processing software is required for raw NMR data files

Estimated total storage size of dataset: Less than 100 megabytes

DOI : 10.17035/d.2017.0038572887

DOI URL: http://doi.org/10.17035/d.2017.0038572887

Related URL: http://www.thebrowneresearchgroup.co.uk

Description

A one-pot, two step mechanochemical synthesis process has been developed, of fluorinated pyrazolones. The experiments here have provided a logical approach to multistep solventless synthesis under milling conditions. This demonstrates the applicability of mechanochemical synthesis to multistep procedures.

Analysis of reaction products from this methodology resulted in the following data:
1H, 19F and 13C NMR raw data files
IR spectra
High-Resolution Mass Spectrography spectra.

Research results based upon these data are published as http://doi.org/10.3762/bjoc.13.189