Teitl: FLP-Catalyzed Transfer Hydrogenation of Silyl Enol Ethers

Dyfyniad
Khan I, Reed-Berendt BG, Melen RL, et al. (2018). FLP-Catalyzed Transfer Hydrogenation of Silyl Enol Ethers. Cardiff University. https://doi.org/10.17035/d.2018.0055962956

Manylion y Set Ddata

Cyhoeddwr: Cardiff University

Dyddiad (y flwyddyn) pryd y daeth y data ar gael i'r cyhoedd: 2018

Fformat y data: .txt, .inmr, .info, .par, .xml, .pdf, .temp, .back, .jpg, .ispd

Meddalwedd ofynnol: An appropriate NMR processing software is required for raw NMR data files

Amcangyfrif o gyfanswm maint storio'r set ddata: Llai nag 1 gigabeit

Nifer y ffeiliau yn y set ddata: 3000

DOI : 10.17035/d.2018.0055962956

DOI URL: http://doi.org/10.17035/d.2018.0055962956

Related URL: http://blogs.cardiff.ac.uk/themorrillgroup/

Disgrifiad

Herein we report the first catalytic transfer hydrogenation of silyl enol ethers. This metal free approach employs tris(pentafluorophenyl)borane and 2,2,6,6-tetramethylpiperidine (TMP) as a commercially available FLP catalyst system and naturally occurring γ-terpinene as a dihydrogen surrogate. A variety of silyl enol ethers undergo efficient hydrogenation, with the reduced products isolated in excellent yields (29 examples, 82% average yield).

Analysis of reaction products from this methodology resulted in the following data:

1H, 19F and 13C NMR raw data files

IR spectra

High-Resolution Mass Spectrography spectra.

Research results based upon these data are published at http://doi.org/10.1002/anie.201808800