Title: FLP-Catalyzed Transfer Hydrogenation of Silyl Enol Ethers

Khan I, Reed-Berendt BG, Melen RL, et al. (2018). FLP-Catalyzed Transfer Hydrogenation of Silyl Enol Ethers. Cardiff University. http://doi.org/10.17035/d.2018.0055962956

Access Rights: Data can be made freely available subject to attribution
Access Method: Click to email a request for this data to opendata@cardiff.ac.uk

Dataset Details
Publisher: Cardiff University
Date (year) of data becoming publicly available: 2018
Data format: .txt, .inmr, .info, .par, .xml, .pdf, .temp, .back, .jpg, .ispd
Software Required: An appropriate NMR processing software is required for raw NMR data files
Estimated total storage size of dataset: Less than 1 gigabyte
Number of Files In Dataset: 3000
DOI: 10.17035/d.2018.0055962956


Herein we report the first catalytic transfer hydrogenation of silyl enol ethers. This metal free approach employs tris(pentafluorophenyl)borane and 2,2,6,6-tetramethylpiperidine (TMP) as a commercially available FLP catalyst system and naturally occurring γ-terpinene as a dihydrogen surrogate. A variety of silyl enol ethers undergo efficient hydrogenation, with the reduced products isolated in excellent yields (29 examples, 82% average yield).

Analysis of reaction products from this methodology resulted in the following data:

1H, 19F and 13C NMR raw data files

IR spectra

High-Resolution Mass Spectrography spectra.

Research results based upon these data are published at http://doi.org/10.1002/anie.201808800 

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Last updated on 2018-23-08 at 08:43