Title: A Ball-Milling Enabled Reformatsky Reaction


Citation
Cao Q, Stark RT, Fallis IA, et al. (2019). A Ball-Milling Enabled Reformatsky Reaction. Cardiff University. http://doi.org/10.17035/d.2019.0075438608



Access Rights: Data is provided under a Creative Commons Attribution (CC BY 4.0) licence

Access Method: Click to email a request for this data to opendata@cardiff.ac.uk


Cardiff University Dataset Creators


Dataset Details

Publisher: Cardiff University

Date (year) of data becoming publicly available: 2019

Coverage start date: 01/06/2017

Coverage end date: 05/01/2019

Data format: .jpg .fid

Software Required: .fid files are processed using standard NMR processing software.

DOI : 10.17035/d.2019.0075438608

DOI URL: http://doi.org/10.17035/d.2019.0075438608

Related URL: https://onlinelibrary.wiley.com/doi/10.1002/cssc.201900886


Description

The data here contains a selection of 1H, 13C, 19F NMR data, as well as IR, MS and any relevant chromatography information. Some files may be processed in advance and deposited and some may require access to typical processing tools for data of this type.
Abstract: An operationally simple one‐jar one‐step mechanochemical Reformatsky reaction using in situ generated organozinc intermediates under neat grinding conditions has been developed. Notable features are that this reaction protocol requires no solvent, no inert gases and no pre‐activation of the bulk zinc source. The developed process is demonstrated to have good substrate scope (39‐82% yield), and is effective irrespective of the morphology of the zinc source.

Research results based upone these data are published at http://doi.org/10.1002/cssc.201900886


Keywords

Mechanochemistry, Organozinc

Related Projects

Last updated on 2020-26-11 at 12:32