Title: Iron-Catalyzed Borrowing-Hydrogen β‐C(sp3)‐Methylation of Alcohols
This data is not currently available because: Intent to publish project results
Cardiff University Dataset Creators
Dataset Details
Publisher: Cardiff University
Date (year) of data becoming publicly available: 2019
Data format: .txt, .inmr, .info, .par, .xml, .pdf, .temp, .back, .jpg, .ispd
Software Required: An appropriate NMR processing software is required for raw NMR data files
Estimated total storage size of dataset: Less than 1 gigabyte
Number of Files In Dataset: 3271
DOI: 10.17035/d.2019.0082983146
DescriptionHerein we report the iron-catalyzed b-C(sp3)-methylation of primary alcohols using methanol as a C1 building block. This borrowing hydrogen approach employs a well-defined bench stable (cyclopentadienone)iron(0) carbonyl complex as precatalyst (5 mol %) and enables a diverse selection of substituted 2-arylethanols to undergo b-C(sp3)-methylation in good isolated yields (24 examples, 65% average yield).
Analysis of reaction products from this methodology resulted in the following data:
1H, 19F and 13C NMR raw data files
IR spectra
High resolution mass spectrometry spectra.
Research results based upon these data are published at http://doi.org/10.1021/acscatal.9b02461.