Title: N-Heterocyclic Carbene Acyl Anion Organocatalysis by Ball-Milling


Citation
Nicholson W I, Seastram AC, Iqbal SA, et al. (2019). N-Heterocyclic Carbene Acyl Anion Organocatalysis by Ball-Milling. Cardiff University. http://doi.org/10.17035/d.2019.0087455694



Access Rights: Data is provided under a Creative Commons Attribution (CC BY 4.0) licence

Access Method: Click to email a request for this data to opendata@cardiff.ac.uk


Dataset Details

Publisher: Cardiff University

Date (year) of data becoming publicly available: 2019

Coverage start date: 01/06/2017

Coverage end date: 02/09/2019

Data format: .jpg .fid

Software Required: .fid files are processed using standard NMR processing software.

DOI : 10.17035/d.2019.0087455694

DOI URL: http://doi.org/10.17035/d.2019.0087455694

Related URL: https://onlinelibrary.wiley.com/journal/1864564x


Description

The data here contains a selection of 1H, 13C, 19F NMR data, as well as IR, MS and any relevant chromatography information. Some files may be processed in advance and deposited and some may require access to typical processing tools for data of this type.
Abstract: The ability to conduct N-Heterocyclic carbene catalysed acyl anion chemistry under ball-milling conditions is reported for the first time. This process has been exemplified through applications to intermolecular-benzoin, intramolecular-benzoin, intermolecular- Stetter and intramolecular-Stetter reactions including asymmetric examples and demonstrates that this mode of mechanistically complex organocatalytic reaction can operate under solvent minimised conditions.

Reserach results based upon these data are published at https://doi.org/10.1002/cssc.201902346


Keywords

Mechanochemistry

Related Projects

Last updated on 2020-03-12 at 14:40