Title: N-Heterocyclic Carbene Acyl Anion Organocatalysis by Ball-Milling
Citation
Nicholson W, Seastram AC, Iqbal SA, et al. (2019). N-Heterocyclic Carbene Acyl Anion Organocatalysis by Ball-Milling. Cardiff University. https://doi.org/10.17035/d.2019.0087455694
Access Rights: Creative Commons Attribution 4.0 International
Access Method: Click to email a request for this data to opendata@cardiff.ac.uk
Cardiff University Dataset Creators
Dataset Details
Publisher: Cardiff University
Date (year) of data becoming publicly available: 2019
Coverage start date: 01/06/2017
Coverage end date: 02/09/2019
Data format: .jpg .fid
Software Required: .fid files are processed using standard NMR processing software.
DOI : 10.17035/d.2019.0087455694
DOI URL: http://doi.org/10.17035/d.2019.0087455694
Related URL: https://onlinelibrary.wiley.com/journal/1864564x
The data here contains a selection of 1H, 13C, 19F NMR data, as well as IR, MS and any relevant chromatography information. Some files may be processed in advance and deposited and some may require access to typical processing tools for data of this type. Reserach results based upon these data are published at https://doi.org/10.1002/cssc.201902346
Description
Abstract: The ability to conduct N-Heterocyclic carbene catalysed acyl anion chemistry under ball-milling conditions is reported for the first time. This process has been exemplified through applications to intermolecular-benzoin, intramolecular-benzoin, intermolecular- Stetter and intramolecular-Stetter reactions including asymmetric examples and demonstrates that this mode of mechanistically complex organocatalytic reaction can operate under solvent minimised conditions.
Keywords
Mechanochemistry
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