Title: N-Heterocyclic Carbene Acyl Anion Organocatalysis by Ball-Milling

Citation
Nicholson W I, Seastram AC, Iqbal SA, et al. (2019). N-Heterocyclic Carbene Acyl Anion Organocatalysis by Ball-Milling. Cardiff University. http://doi.org/10.17035/d.2019.0087455694


Access Rights: Data is provided under a Creative Commons Attribution (CC BY 4.0) licence
Access Method: Click to email a request for this data to opendata@cardiff.ac.uk

Dataset Details
Publisher: Cardiff University
Date (year) of data becoming publicly available: 2019
Coverage start date: 01/06/2017
Coverage end date: 02/09/2019
Data format: .jpg .fid
Software Required: .fid files are processed using standard NMR processing software.
DOI: 10.17035/d.2019.0087455694

Description

The data here contains a selection of 1H, 13C, 19F NMR data, as well as IR, MS and any relevant chromatography information. Some files may be processed in advance and deposited and some may require access to typical processing tools for data of this type.
Abstract: The ability to conduct N-Heterocyclic carbene catalysed acyl anion chemistry under ball-milling conditions is reported for the first time. This process has been exemplified through applications to intermolecular-benzoin, intramolecular-benzoin, intermolecular- Stetter and intramolecular-Stetter reactions including asymmetric examples and demonstrates that this mode of mechanistically complex organocatalytic reaction can operate under solvent minimised conditions.


Keywords

Mechanochemistry

Related Projects
Homogeneous hydrogen transfer catalysis (01/10/2016 - 30/09/2019)

Last updated on 2019-22-11 at 16:24