Professor Francis Lai
Projects as PI
- Produce novel forms of recombinant PLC-zeta (hPLC) suitable for development as a potential therapeutic for IVF/ICSI procedures (01/03/2016 - 31/10/2017)
- Professional training year placement students (01/09/2014 - 31/08/2015)
- Research scholarship in cardiovascular research techniques from molecule to man (01/07/2010 - 30/09/2018)
- Role of PLC-zeta in generating Ca2+ oscillations and triggering egg activation at fertilization (01/07/2007 - 30/06/2011)
- Structural analysis of the mTOR kinase domain by X-ray crystallography (01/10/2009 - 30/04/2013)
Projects as Co-Investigator
- Application of the sperm factor phospholipase C zeta (PLCz)mediated calcium oscillations at fertilization to improve the efficacy of assisted reproductive technology (ART) (01/01/2015 - 31/12/2019)
- Deciphering the serum-borne triggers of ryanodine receptor dysfunction in juvenile sudden cardiac death (01/01/2007 - 31/12/2009)
- Drug induced stabilisation of RyR2 to improve calcium handling and cardiac function in inherited and acquired cardiac disease (15/09/2015 - 30/09/2020)
- Human cardiac ryanodine receptor in arrhythmias and sudden cardiac death: Role of inter-subunit interactions 2 (01/07/2009 - 30/06/2014)
- Signal transduction of Ca2+ oscillations in eggs at fertilization (01/12/2009 - 30/09/2013)