Professor Simon Ward
Projects as PI
- An integrated target validation and drug discovery platform for the identification of novel agents targeting genome stability for the treatment of cancer (01/01/2021 - 30/06/2022)
- KAT2A/B PROTACs targeting differentiation in leukemic Stem Cells and blasts for the treatment of AML (01/01/2024 - 31/12/2025)
- LIMK1 inhibitors - A novel, disease-modifying approach for the treatment of fragile X syndrome (01/05/2019 - 31/12/2021)
- Mechanisms of aminoglyscoside ototoxicity and drug damage repair in sensory hair cells: Towards the design of otoprotective strategies (01/08/2017 - 31/03/2019)
- Non-Ubiquitin mediated targeted degradation of pathogenic protein aggregates (01/10/2021 - 31/03/2025)
Projects as Co-Investigator
- Allosteric modulators of extrasynaptic GABAA receptors for the treatment of postpartum depression (01/01/2022 - 30/06/2024)
- Allosteric modulators of spinal cord glycine receptors for the treatment of chronic pain (01/02/2023 - 31/01/2025)
- Alpha-GABAa receptor modulators for the treatment of cognitive impairment associated with Huntington's disease (01/08/2017 - 30/09/2022)
- Cardiff Translational Drug Discovery Centre (CTDDC) (01/09/2017 - 31/08/2022)
- Developing non-covalent acid ceamidase inhibitors to treat Krabbe disease (01/01/2024 - 31/12/2025)