Teitl: Cellular and extracellular aspects of posterior eye microstructure and biomechanics

Engineering and Physical Sciences Research Council

Prif Ymchwiliwr

Manylion y Prosiect
Dyddiad dechrau: 01.10.2016
Dyddiad gorffen: 30.04.2020

A quarter of the entire human population is affected by vision disorders, with extensive efforts directed towards developing new and improved treatments. The peripapillary sclera (PPS) has a large influence on the forces exerted on the optic nerve under fluctuating intraocular pressure (IOP), implying a role in the mechanics of glaucoma. To better comprehend these processes, physiologically relevant data were collected on both the scleral extracellular matrix (ECM) and cell cytoskeletal components. The cytoskeletal architecture was reconstructed using a novel approach for generating geometrically accurate models for finite element (FE) analysis.

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Diweddarwyd y tro diwethaf ar 2020-12-10 am 15:42