Title: Development and evaluation of selective allosteric calpain-1 inhibitors

Engineering and Physical Sciences Research Council

Principal Investigator

Cresser-Brown, Joel

Allemann, Rudolf
Miller, David

Project Details

Start date: 01/01/2016

End date: 31/12/2019


Exploring and
evaluating the development diselenoacrylates as redox stable allosteric
calpain-1 inhibitors based upon previous α-mercaptoacrylate
analogues, as well as the structure guided computational design and
validation of novel calpain-1 inhibitors.

Related Datasets

Last updated on 2018-05-11 at 12:27