Teitl: Quantitative spatio-temporal study of single membrane proteins and lipid domains with label-free super-resolution optical microscopy
Arianwyr
Engineering and Physical Sciences Research Council
Prif Ymchwiliwr
Cyd-Ymchwilwyr
Langbein, Wolfgang
Borri, Paola
Manylion y Prosiect
Dyddiad dechrau: 01.10.2015
Dyddiad gorffen: 31.03.2019
Crynodeb
Using
quantitative differential interference contrast microscopy, optical thickness
maps of lipid bilayers are generated which enable the visualisation of lipid
bilayers, including lipid domains, without the need to incorporate
fluorescent probes into the bilayer structure. Using the known refractive index
of lipid bilayers, the optical thickness maps can be used to obtain the
absolute thickness of the lipid bilayers with sub-nanometre precision.
Setiau Data Cysylltiedig
- Lipid bilayer thickness measured by quantitative DIC reveals phase transitions and effects of substrate hydrophilicity - data (2019)
- Measuring sub-nanometre thickness changes during phase transitions of supported lipid bilayers with quantitative differential interference contrast microscopy (2019)
- Quantitative label-free imaging of lipid domains in single bilayers by hyperspectral coherent Raman scattering - data (2020)
