Teitl: A computational study exploring the molecular basis of anaesthesia

Arianwyr
Engineering and Physical Sciences Research Council

Prif Ymchwiliwr

Cyd-Ymchwilwyr
De Leeuw, Nora

Manylion y Prosiect
Dyddiad dechrau: 02.04.2018
Dyddiad gorffen: 31.03.2022
Crynodeb

This project aims to develop and employ state-of-the-art computational chemistry methods to investigate the electronic structure and geometrical parameters of a range of anaesthetic

substances to gain a fundamental understanding of their mode of action, based on their physical and chemical properties, in a realistic metabolic environment. We also aim to explore the interactions between the cell receptor and the anaesthetic molecules to investigate the chemical and thermodynamic properties of binding to key structural sites of functional inhibition.


Diweddarwyd y tro diwethaf ar 2019-18-07 am 13:19